Can anyone share their experience with Pluvicto?

Some people react too strongly to Pluvicto and can’t continue with it.

Other people need to have a lower dose or have more time between Infusions.

You need to talk to your radiation oncologist about this problem. It is a very strong reaction and unusual. Get the doctor’s opinion on what to do next.

I'm 74 and have had stage 4 gleason 9 for 7+ years, and am on hormone therapy with a total of 45+ days of radiation. So far God's blessed me with a great oncologist and a great radiologist. Each time the identified areas of metastasized get addressed.
now I started my PLUVICTO treatment and only 14 days out and I still feel like crap. Max fatigue. Almost like my muscles and bones don't want to operate anymore. I can go for a daily 2 mile walk and I'm wiped out through 1/2 of the day. The last 4 days seems to have impacted my bowel movement as I have had to use the bathroom about every 30-40 minutes. Stools have been very very muddy (sorry to share). I'm getting about an average of 5 hrs sleep a nite and sruggle to fall asleep (if a all) again.
Nausea that just won't go away. I actually believe the anti nausea meds makes me feel worse. My next treatment is around Dec 21 (Merry Christmas!) and maybe i'll get a surprise gift.

@jimw77

thank you for your good thoughts. Pluvicto is on hold due to other medical issues, and yes, one day at a time and it all belongs to Him.

@michaelbryan6998
Michael, I hope that you've now had that fourth round of Pluvicto and the PSMA PET scan is now scheduled. I'm 77 years young, extensive mets, heart and other comorbidities, but taking it all as it comes and making the most of each day. Keep on keeping on.

@shz
Got to admit, that’s a lot of genetic issues.

Are all 4 really found in one person?

I would not even try to make a guess.

@jeffmarc
What if you have PTen and TP53 as well as ATM and BRCA?

Radiation was discovered 130 years ago and the scientists fully understand the positive and negative effects on animals and plants. You are correct, no clinical trials was performed specifically on "pets". Why would an institution spend hundres of millions of dollars to do so? We understand radiation. But, a pet is an animal and it's been know for a century the harm LU-177 can have.
I was one of the original Pluvicto clinical trial patients and hold multiple science degrees with 50 years of real life experience. You can do whatever you want, but raiation can be very helpful and deadly dangerous. It's basic physics, not "misinformation".

Again I ask you to show me the clinical trails that mention pets, there are none. thats the science stop passing out misinformation

To eugenelapietrial:
I believe your basic knowledge of the science and understanding of radiation is way off. Pluvicto uses beta particle. Although the exchange of bodily fluids should avoided for a predetermined time after a Pluvicto treatment, this includes exhaling water vapor, saliva, urine, sweat, etc. But, as with all radioactive particles, the particles of beta, gamma, etc. travels through the atmosphere. That's the basics of a sunburn (UV radiation), a medical x-ray or CT, scan, the atomic bomb, etc. I carry a small geiger counter with me after each Pluvicto treatment and can easily see and hear the radiation levels being emitted from my body. No bodily fluids required. The radioactive particles are emitted through the skin.

I more that qualify and start LU 177 early Oct as it takes 2 weeks to come form USA NJ or new plant in Indianapolis In Canada its covered for over 65 and if you do ALL the tests Its in my bones only Pray for success They say it costs $27K per each of 6 injections