Can anyone share their experience with Pluvicto?

@colleenyoung Thanks, Colleen, for looping me in. Dear Rose: My husband was able to walk and move about on his own during Pluvicto. He was treated at Mayo Rochester, whose safety instructions were much less strict than those reported by some other people posting here. We were not told to keep three feet apart for any length of time, but we were advised to use separate beds and bathrooms for a couple of days after an infusion if possible. As Colleen suggests, you can ask your father's care team for specific instructions on how you can care for your father but still observe sufficient precautions after his infusions. Simply telling you to "do the best you can" isn't helpful. Good luck with getting some additional help from his providers. Sending love and strength to you....

@ewatson201 I don't want anyone to decline Pluvicto on the grounds that they can't afford it. For many in the U.S., it is covered by insurance. I don't know where you live or what kind of insurance you have, but my husband had six Pluvicto infusions in 2024 and the cost was entirely covered by original Medicare and an Anthem Medicare supplement made available to retirees by our university. So while it is a good idea to check coverage, don't assume Pluvicto isn't ever covered.

My husband was told after 10 rounds of radiation that Pluvicto was the only option. He also had Spinal Stenosis. Has anyone told you how much the Pluvicto is extremely beyond expensive. After insurance it was $30000 a round. My husband passed at 76 on April 25th. We had a surprise bill as we're never told how much it was. Be careful. It's still a 30-30-30 success rate. Wishing the best.

Thanks, @colleenyoung

Hi, @rosedl. I didn't have Pluvicto, so the 3-foot distancing wasn't an issue, but I can comfirm that someone with paralysis due to a spinal lesion does need a very high level of close care, from rolling them on their side to prevent pressure injuries (bedsores), to assisting them in and out of a wheelchair, to giving them their meds, to emptying their bedpan or commode chair. There's no way you can do all that from 1 metre away, so you'll need to have an urgent conversation with your father's medical team about how to minimise your own risk.

My background:

I was 56 when I was paralyzed from the ribs down due to a prostate cancer metastasis to my spine in 2021. They did emergency debulking sugery to the lesion, then post-op radiation, and later radiation to the prostate itself. They also started me immediately on hormone therapy (ADT and Apalutamide).

I defied the odds and got back to walking (with various issues/adaptations) after a couple of years of demanding physio. If it was a near-run thing for me starting at 56, I understand why it would be nearly impossible for your father at 81.

I wish the best to both of you. ❤️

@rosedl, welcome. I'm bringing @northoftheborder into this conversation to address your question about not being able to walk due to metastasis. @lag is a caregiver for someone who received Pluvicto.

Rose, have you spoken to you father's care team about adaptations to the distancing precautions that you can make and provide care for your dad?

I am sorry to hear about your issue but I cannot answer your question.

Following this as my 81 y.o. father just received injection 1 of 6 today. Wondering if anyone else has been a caretaker with someone currently unable to walk due to metastases and how you handle/handled the 3 feet distance and what precautions or extra steps you took or suggest as most of the guidelines are simply impossible and were advised to do the best we can. Thanks in advance for reading.

I am 72 and had prostate removal over 20 years go, but the cancer returned, as often happened. Had my sixth pluvicto two weeks ago (never had chemo before, Nubeca was no longer working to suppress PSA). The side effect that got to me--beyond dry mouth---was decreasing to the point that I faint in someone's garage. I had no idea, thinking it was general fatigue as described. No ocular or bone structure damage but I was hospitalized overnite (plus hospital at home one nite) but the right side of my face above the cheek is a horror movie. I am grateful that it was only that. I will add I have not been hospitalized in at least 30 years and I got the worst sleep in my life in the place.

Thank you

I moved your question about Pluvicto to this related discussion:
- Can anyone share their experience with Pluvicto? https://connect.mayoclinic.org/discussion/can-anyone-share-their-experience-with-pluvicto/

See all Pluvicto related discussions using Search here: https://connect.mayoclinic.org/group/prostate-cancer/

@ewatson201, is Pluvicto being recommended for you? Are you scheduled to start treatment?