CA 27-29 numbers rising: Does anyone else have an issue like this?

Posted by sandyjr @sandyjr, Jul 1, 2019

My Ca 27.29 seems to be high….in the 40’s….and my oncologist says that that is probably normal for me. He checked the records from my first bc. Does anyone else have an issue like this?

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@resort

Hope you continue to do well. Have you tried other non conventional ways yet like diet? There are books talk about how other patients miraculously have radical remission after changing diet. God bless you and many hugs to you!

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@tessspike Hi and thanks for the hugs. Diet is absolutely something that can be worked on and glad you brought it up. And exercise! But diet…I advocate a common sense approach which my docs – primary and cancer agreed on. I cut way back on sugar – medical opinion is mixed but hey those tests that require a glucose solution to help identify cancer cells is all one needs for affirmation that lots of sugar can’t be good for someone. I try to go more organic/ natural because growth hormones or lots of antibiotics possibly could contribute to cell growth or reduced resistance. I drink lots more water, seltzer and am mindful of my alcohol. And I take a variety of vitamins. I have lost weight slowly and carefully which has contributed to lower blood pressure . I am not fixated and can enjoy a steak or ice cream – this is a marathon, not a sprint for me. And I am probably the only person who did not lose weight on Verzenio or during 20 rounds of chemo – thanks to friends who made me gallons of soup. Hand in hand was exercise. I started walking the day after my double mastectomy and kept it up at my chemo treatments in the hallways and outside in the parking lot. Yoga and Pilates were two new exercises I started to help gain back flexibility and strength in my arms and to lessen bone and joint pain. And I swam – which I hate – but my surgeon said it would be good for my arms and lessen my lymphatic fluid build up. My husband is doing yoga and Pilates with me and surprise – his persistent back is gone. I have to learn to live with my cancer and my docs are realistic that it will probably come back at some point. All I can do is be at my best – bloodwork, physically, spiritually and mentally. I hope to positively impact what I can control/influence and then let the docs or the rest of my team do their part. Good luck to you as well!

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@keepmoving2

@tessspike. Good for you for being on top of your numbers. I am a big advocate on this site for tracking all your numbers on a chart for two reasons: 1) it helps a patient to know what is going on with their body & 2) to see trends. In your case, absolutely the knee replacement surgery can impact numbers. It might be helpful to track all your numbers a bit further back to day one. Maybe talk to your doctors to get a sense of when you can expect the surgery impact to lessen or request /look at your other numbers to see if the inflammation/surgery is reflected elsewhere. Docs like to see trends and like you pointed out, backup with scans, how you are feeling, etc. Fingers crossed for you. I am going on my 4th year as a MBC patient and have rebounded really well from when my initial meds stopped working 18 mos in. 2nd meds didn’t work but this third round seems to be doing the trick!

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Hope you continue to do well. Have you tried other non conventional ways yet like diet? There are books talk about how other patients miraculously have radical remission after changing diet. God bless you and many hugs to you!

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My CA27-29 has been a bit up and down but trending up . It
Was 41.5 6/21 a month after double mastectomy
was 36.3 12/21/21
It is now 53.5 01/19/23
Just got that result haven’t spoken to oncologist yet to see if he has ideas. Haven’t had the CA15-3 yet, imagine that may be next. Trying not to jump to conclusions.

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@keepmoving2

@tessspike. Good for you for being on top of your numbers. I am a big advocate on this site for tracking all your numbers on a chart for two reasons: 1) it helps a patient to know what is going on with their body & 2) to see trends. In your case, absolutely the knee replacement surgery can impact numbers. It might be helpful to track all your numbers a bit further back to day one. Maybe talk to your doctors to get a sense of when you can expect the surgery impact to lessen or request /look at your other numbers to see if the inflammation/surgery is reflected elsewhere. Docs like to see trends and like you pointed out, backup with scans, how you are feeling, etc. Fingers crossed for you. I am going on my 4th year as a MBC patient and have rebounded really well from when my initial meds stopped working 18 mos in. 2nd meds didn’t work but this third round seems to be doing the trick!

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Thank you so much! That is such encouraging information. I do track my numbers, and my oncology team has an excellent portal where I can do that. I do some strenuous PT every day for the knee so I'm hoping that might be it. I'm so thankful for you that that third round of meds is working for you!

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@tessspike

I am stage 4 ILC, doing well after a year of treatment on ribociclib, fervescent, and zomata, with numbers falling generally and clear scans. My CA 27-29 has been in the 32 range for 2 months, but this month jumped to 40. I have had knee replacement surgery and a stomach bug in the meantime and on various meds. Is this number ever effected by other situations/conditions? I know the CEA can be affected by inflamation. And it has stayed level at 10.

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@tessspike. Good for you for being on top of your numbers. I am a big advocate on this site for tracking all your numbers on a chart for two reasons: 1) it helps a patient to know what is going on with their body & 2) to see trends. In your case, absolutely the knee replacement surgery can impact numbers. It might be helpful to track all your numbers a bit further back to day one. Maybe talk to your doctors to get a sense of when you can expect the surgery impact to lessen or request /look at your other numbers to see if the inflammation/surgery is reflected elsewhere. Docs like to see trends and like you pointed out, backup with scans, how you are feeling, etc. Fingers crossed for you. I am going on my 4th year as a MBC patient and have rebounded really well from when my initial meds stopped working 18 mos in. 2nd meds didn’t work but this third round seems to be doing the trick!

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@tessspike

I am stage 4 ILC, doing well after a year of treatment on ribociclib, fervescent, and zomata, with numbers falling generally and clear scans. My CA 27-29 has been in the 32 range for 2 months, but this month jumped to 40. I have had knee replacement surgery and a stomach bug in the meantime and on various meds. Is this number ever effected by other situations/conditions? I know the CEA can be affected by inflamation. And it has stayed level at 10.

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Yes! My oncologist indicated numbers can go up for a multitude of reasons including inflammation, diet, alcohol, strenuous exercise, even being out in the night air for me. ♥️

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I am stage 4 ILC, doing well after a year of treatment on ribociclib, fervescent, and zomata, with numbers falling generally and clear scans. My CA 27-29 has been in the 32 range for 2 months, but this month jumped to 40. I have had knee replacement surgery and a stomach bug in the meantime and on various meds. Is this number ever effected by other situations/conditions? I know the CEA can be affected by inflamation. And it has stayed level at 10.

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@sam2020

Peggie,
Thank you so much for sharing. I was in a group through Cancer Care, but was only allowed to be in the caregiver group, and most of the people were the wives of men that had other types of cancer, I prefer to talk with people that share our journey and understand MBC, and the lab tests, scans and results. I have been reading posts to my wife, hoping to encourage her to join. She has a great support system of family and friends, but no one can really know what she is going through. As you are entering year four post diagnosis, I hope your quality of life is good. Jen's days are like a roller coaster, but thankfully the past few days have been good. We feel blessed that she has good days. I hope you don't mind me reaching out, thank you.
Sam

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Good morning again, Sam. I'm not sure how Mayo works and maybe Colleen who oversees this can chime in. I'm in another group on another site where we can 'friend' people so we can discuss topics or our situations one on one rather than take up room on other's conversations; share e-mails and such. I don't want to go against this site's rules. So maybe Colleen can let us know if there is a way to do this. I like being of help if I can or just a sounding-board or good ear for listening. None of us know from month to month and sometimes day to day how things will change. I am up and about, although haltingly hoping my femur mets in my left leg are helped by radiation that will wrap-up Wednesday. Then I can deal with a blocked femoral artery in my right. I laugh at this only because "if it's not one thing it's another". Please reach out anytime.
I hope you and Jen can have a relaxing holiday with family and friends.
Peggie

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@mom23boys

Hi Sam. I'm so sorry your wife is going thru such issues; much more than I had imagined. Having a bit of her history now it becomes much clearer. I've had the same base of skull and C2 – C7 issues. They have waffled between 2 spots that lit up on my bone scan, thinking metastasis to arthritis. I also have compressed discs but have not, thankfully, suffered any fractures. I don't have any real experience in that area but it sounds like her doctors are on top of it with treatments to try to control the pain. As far as the radiation, they were thinking of doing my neck but decided to wait and see if there are any changes. They had forewarned me that there would be some temporary side-effects to the Esophagus (a couple weeks of a burning type feeling). I know others who have had radiation to other areas of the spine/ribs that unfortunately have that same effect along with some heartburn type feeling. We are all different though and as such may or may not suffer the same effects.
I do not have LDH or CEA tests. Also, I was diagnosed stage 4 in April of 2019 although I had never been early-stage.
Feel free to communicate if you like or if your wife would like someone to talk to.
Peggie

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Peggie,
Thank you so much for sharing. I was in a group through Cancer Care, but was only allowed to be in the caregiver group, and most of the people were the wives of men that had other types of cancer, I prefer to talk with people that share our journey and understand MBC, and the lab tests, scans and results. I have been reading posts to my wife, hoping to encourage her to join. She has a great support system of family and friends, but no one can really know what she is going through. As you are entering year four post diagnosis, I hope your quality of life is good. Jen's days are like a roller coaster, but thankfully the past few days have been good. We feel blessed that she has good days. I hope you don't mind me reaching out, thank you.
Sam

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@adanab

Hi Sam. Sorry you and your wife are having to deal with a stage 4 MBC. I received that same diagnosis 1 1/2 yrs ago, a recurrence from 2006. I’m mets to the bones (everywhere, mostly pelvis, legs, spine) and liver. My onco said that I lite up like a Christmas tree on my first PET scan. At that time my 27/29 was in the 2000’s. We got it down to the 600’s pretty quick with Ibrance/Faslodex, and when they stopped working with Afinitor/can’t recall the combo (post menopausal meds). The 27/29 never went below 300’s. We use the 27/29 as an indicator only and rely on a scan of some sort for a diagnoses. I’m curious that your onco is using CT scans whereas mine relies on PETs and your wife and I have the same diagnosis? If you think the CT is possibly missing something you could ask for a PET.
Fatigue is a constant (extreme) and I agree with another reply that it comes from a combo of the meds, pain/extreme discomfort, and in my case the inability to walk well let alone exercise. I don’t think there’s much that can be done to improve fatigue. It was suggested to me that I might be depressed which wasn’t the case but I can certainly see how it’s possible. All the best to you both.
Adana

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Adana,
I'm sorry to hear of your situation. I'm floored that your 27-29 was in the 2000's, I didn't even realize that the numbers got that high. I can't imagine being in your situation and not being depressed, thankfully my Jen has a great support system of family, friends, antidepressants, and myself to help keep pull her up when she gets down. To answer about the scans, she gets them every three months. She was started with a PET scan, and has had three over the past two years, there have been a lot of MRI's, and the last four sets of scans have been CT's and whole body bone scans. I don't know how her Onc decides which types of scans need to be done, but that is a great question to ask next visit. I hope you have someone by your side during your journey.
Sam

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