Breathing restriction after nebulizing 7% solution?

Posted by lenorj @lenorj, May 26 8:00am

My pulmonologist prescribed nebulizibg 7% solution twice a day. I am able to move and remove mucus but find that my chest feels constricted and breathing more difficult after the treatments. Has anyone else had this reaction?

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Are you using albuterol or levalbuterol before nebbing the saline?

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@lenorj - Do you possibly have asthma or reactive airways in addition to bronchiectasis? Sometimes 7% can be too strong and cause spasms. Maybe you can ask to try 3% saline & work your way up to a stronger dose.
Sue

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I do have some asthma, although I haven’t had much trouble with it. Does the 3% produce the same negative bacterial environment that I have read so much about in the forum?

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@lenorj

I do have some asthma, although I haven’t had much trouble with it. Does the 3% produce the same negative bacterial environment that I have read so much about in the forum?

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Lower saline strengths do not have as much effect on NTM, but some people on this group have had success tolerating starting with 3% and gradually increasing strength by mixing with 7%. In addition to effectiveness in suppressing bacteria growth, there is good evidence that 7% saline is better at thinning mucus than airway clearance (ACT) alone, a bronchodilator plus ACT or a bronchodilator plus .9% saline and ACT.
https://www.sciencedirect.com/science/article/pii/S0954611104002057

My pulmonologist says with "stable bronchiectasis" (no active infection and no recent exacerbations) As my primary would say "something is better than nothing." I am not sure I need all 4-5 ml in one sitting, it is just the "traditional" size of vials made for nebulized substances. I stop nebbing when I am getting up the mucus, then rinse and gargle with plain water. Someday I hope to find a study that talks about how much is is really necessary.

Have you tried using your asthma inhaler before nebbing? Sometimes that helps with the tight feeling.
Sue

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Thank you for all the good advice and the supportive link. I will try to digest all of this and review all of my options. You have been a great help. I’m

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I also use 7% saline. But always do a levabuterol (xopenx) aerosol first. This is what was prescribed. But I decided to try it without doing the levabuterol first and I got exactly the same the reaction you described (short of breath and chest tightness). Now I never do the saline without the levabuterol or albuterol (if works for you) first.

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So far I have had good success if I mix of the 3% and the 7%(total 4 ml). I am trying to avoid the use of inhalers if possible. I hope to gradually build up to the full 7%. Thanks for sharing your experience I will keep it as my next alternative.

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