Bone Marker Results - What do they mean?
Can anyone offer information on what my test results mean? I have an appt with my Endo in a week. I am 74 years old and have never taken any bone drugs, although my osteoporosis is considered severe. Thanks.
Bone Alkaline Phosphatase, Result 20
B-CTx Beta Cross Laps, Result 781
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Hi daisy17.
BAP measures an enzyme from the cells that build bone.
B-CTx Beta Cross Laps measures residue left in the blood when your bones are breaking down.
There may be a legend on your report which tells you what numbers are normal for your age and sex.
The numbers vary for different laboratories,
It looks like your BAP is on the low end of normal. And your CTX is on the high end of normal. Which could indicate that you are losing bone.
But, with a recent fracture, CTX is released into the bloodstream making the number less useful as an indicator of bone loss in relation to bone gain.
The purpose of this test, now, before starting a medication, is not to gage loss vs gain. These test results establish a baseline so that you and your doctor can gage whether the medication you take is working for you in a few months when you'll repeat the labs.
Without regard to these numbers, your endocrinologist will be offering you a medication to make your bones stronger.
You might want to look at these medications to see which you'd prefer in advance of the appointment. You will probably be offered: Forteo, Tymlos, Reclast, Evenity or Prolia.
I'm a couple of months younger than you are, and Forteo was my choice two years ago. I find it a wonder drug.
If you want information on these medications, I'm happy to give you my take. Some want their doctors to decide; I never do.
Hi @daisy17 , on your lab report, what's the unit for Bone Alkaline Phosphatase? Different labs may use different units, such as IU/L or mcg/L, which may influence the interpretation.
I agree with @gently , your CTX is on the high side and she explained quite in detail what these bone turnover markers meant and their usage clinically.