Blood Pressure Spike: Anyone experience this after Eligard or Lupron?

I was in a clinical trial for 13 with lupron and Erleada and my blood pressure went up. My cardiologist upped my blood pressure meds. I have been off of lupron and Erleada now for a year and my blood pressure meds needed to be reduced.

I am on eligard and abiraterone and monitoring blood pressure is a daily activity, fortunately i have not had any increase, but it is definitely a potential side effect. Hope you are able to resolve, thank you for sharing. Keep the faith

While I didn’t see a spike in my BP. After I received my first two eligard shots, I was in to have Space Oar gel inserted and my sharp eyed nurse saw a squiggle on my ekg and she freaked. All of a sudden, and I never had any issues, I had to go to emergency for Afib. Saw a cardiologist and he had no concerns, just prescribed Elliquis. I received a total of three shots and rang the bell in May. So far I have not seen anymore incidents. Hormone therapy sucks.

@ddl, I hope you saw the helpful replies from @slick65 @edmond1971 and @hbp. It's not uncommon to have multiple conditions that need monitoring while in cancer treatment. I'm not sure where you are getting treatment, but you may ask about a cardio-oncology specialist or department.

Mayo Clinic offers a program to address heart problems associated with cancer treatment called cardio-oncology or for people who have a pre-existing heart condition when diagnosed with cancer. The Cardio-Oncology Clinic (https://www.mayoclinic.org/departments-centers/cardio-oncology-clinic/overview/ovc-20442193) evaluates people prior to cancer treatment and patients who have experienced side effects due their treatment, and can help evaluate treatment when you have both cancer and heart conditions.

Do you have access to a similar cardio-oncology program? Is your oncologist aware of your cardio issues and vice versa?

I'm on Eligard. My blood pressure was high before treatment. After radiation to spin and ribs, ADT, Darolutamide, and 10 Docetaxel cycles my Blood Pressure runs around 108/78. My wife thinks that the vessels were being compressed. The treatment relieved any compression of my blood vessels and things are good. I also exercised (walking), stairs as much as I can handle.

I have been on adt for 4 months now, the other day I was feeling fatigued, headache and chills, and BP was 160/85 121bpm, I felt better a few hours later

@alandp

Is ADT the only drug you are on? I know that Zytiga can cause some of the issues you have mentioned. You really need to see your doctor about this. Your PCP can recommend a cardiologist if you don’t have one already to work with.

I was having a problem with my pulse, being too high When doing almost nothing and started on metoprolol Which has kept it pretty low, even when I exercise. I am on two other blood pressure medication’s twice daily because of high blood pressure from Zytiga. It could be that ADT alone could do this to you.

The fatigue from ADT can usually be helped a lot by doing exercise. It sounds like counterproductive, but it actually works to go out running or walking and doing weight training. Of course you don’t want to have blood pressure problems and high pulse being excessive when doing exercises.

My blood pressure has also increased since being on Lupron. Not high enough to need meds however.

For six decades (15-75) my BP was 123/78. Six months after RALP, my oncologist put me on Lupron + Abiraterone. For the first year, my BP was 145/85, then it shot up to 190/90, so my oncologist added Losartan to the mix, & that brought it back down to 140/80. After 2.5 years, on oncologist took be off of all meds. I should have waited a month or so to drop the Losartan, because it briefly spiked again before settling back at 118/78.

This graph is linear, not logarithmic. 🙂