Bi-rads 3 finding, history of autoimmune disease, on biologics

Posted by staciecardmaker @staciecardmaker, Mar 5 2:00pm

I'm 39 years old and have had rheumatoid arthritis and Crohn's disease since before age 2. I've been on biologics for about three decades, then JAK inhibitors for about a decade. Last summer, my doctor found precancerous lesions high in my cervix (after I pushed for more testing based on a gut feeling), unrelated to HPV. A few months ago, I started experiencing severe pain in my left breast, leading to an ultrasound and mammogram. Lab work showed estrogen was extremely elevated. Mammogram results showed Type B breast density, "benign-appearing" calcifications in both breasts, no architectural distortion, and no dominant mass or malignant calcifications. However, the ultrasound found a small subcentimeter echogenic (hypoechoic) lesion at the 11 o'clock position with poorly defined margins and posterior acoustic shadowing, but no increased vascularity. The report classified it as BI-RADS 3 (watchful waiting). Given my immune-suppressed status and increased cancer risk, I asked if they would consider a biopsy, and the radiologist agreed. Has anyone experienced a similar situation, and what was the outcome?

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@staciecardmaker, did you have the biopsy? Any update?

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