Aromatase Inhibitors: Did you decide to go on them or not?

Posted by nanato6 @nanato6, Oct 12, 2018

Nanaloves: I’m about to start arimidex and just feel that the contraindications , bone issues etc. are overwhelming. I’m 70 years old, dodged a bullet I feel with zero stage DCIS but the follow up is pretty much no different then if it was more aggressive. I’ve just done 33 treatments of radiation and now they advise arimidex as a preventative. I’m not sure with the beginnings of arthritis and lower back. sensitivity already that I should take it. Anyone not take it and not have a recurrence within the 5 years.

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Has anyone decided to discontinue or not even start Aromatase Inhibitors such as Arimidex and pursue a healthier diet including natural Aromatase Inhibitors such as mushrooms? It's my understanding white button mushrooms can inhibit testosterone converting to estrogen by 60% and wonder if this is a viable option for those of us suffering severe AI side effects, along with other cancer-fighting foods and generally healthy Whole Foods diet. TIA

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Thank you! That will be the next option I guess. Quite the journey we are on😄😄😄😄. I met a lady at the oncologists office and she has a recurrence of triple negative with very poor prognosis so “By the Grace of God go I”.

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Profile picture for bluebird70 @bluebird70

I am now going to start letrozole in 2 weeks. Have tried anastrazole and exemestane with major side effects. This will be my 3rd one. So hopefully 3rd time is a charm. If it isn’t then they are ready to try Tamoxifen. So here is 🙏🏽🙏🏽🙏🏽 That this one is the good one.

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Best of luck, Bluebird. I went through a similar process with the various AI's and finally ended up on Tamoxifen in 2019. I've had way fewer side effects.

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I am now going to start letrozole in 2 weeks. Have tried anastrazole and exemestane with major side effects. This will be my 3rd one. So hopefully 3rd time is a charm. If it isn’t then they are ready to try Tamoxifen. So here is 🙏🏽🙏🏽🙏🏽 That this one is the good one.

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I’ve been taking Exemestane for a little over a year now, and it seems better for me than Anastrozole. I also take a magnesium supplement called “Magtein” for brain focus and leg/foot cramps. It seems to really help me. I get the Magtein online from Amazon, as that has been the easiest method to just have it delivered via UPS during this Covid quarantine.

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Profile picture for elizm @elizm

@kathyomaha55 The insomnia from Exemestane was relentless for me (plus swollen feet) so I gave up on it about a month or so ago, but its effect on my sleep is still evident. Only Valerian Root plus melatonin gives me a good night's sleep now. In a few weeks, I'll start Evista (its a SERM like tamoxifen) which also is known to give one insomnia. It'll be interesting to see what happens.... (ugh)

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My oncologist suggested benadryl for the insomnia - but it makes me really groggy the next day. My regular doctor suggested CALM, after she initially discounted the Exemestane as causing the insomnia. It was relentless for me too. The Calm for sleep really does the trick for me & I take it every night. Wishing you all the best.

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Profile picture for sparklegram @sparklegram

Eliz, do you take these daily or just when you are having problems with leg cramps?

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@spaklegram I take them daily. For me, that's the max. of magnesium which I can tolerate without a laxative effect. (You may want to ease into that amount and see how your body reacts?) My PCP suggested adding the calcium as it, too, helps with cramping.

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Profile picture for kathyomaha55 @kathyomaha55

CALM comes in powder which you dissolve in water & drink, or gummies. I have tried both. The powder is 325 mg in 2 teaspoons. It's also a laxative (just FYI). I also bought the CALM for sleep (as insomnia is one bad side effect I have from Exemestane) and it has melatonin added as well as magnesium. 2 gummies of the Sleep formula is 50 mg magnesium, 3 mg melatonin and 50 mg of L-Theanine (an amino acid) that helps relax you. The Calm Sleep really helps me.

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@kathyomaha55 The insomnia from Exemestane was relentless for me (plus swollen feet) so I gave up on it about a month or so ago, but its effect on my sleep is still evident. Only Valerian Root plus melatonin gives me a good night's sleep now. In a few weeks, I'll start Evista (its a SERM like tamoxifen) which also is known to give one insomnia. It'll be interesting to see what happens.... (ugh)

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Profile picture for elizm @elizm

@sparklegram
Like others, I get occasional leg/foot cramps at night as well and I take 100mg of magnesium and 250mg of calcium citrate-malate, both twice a day for it. It seems to help.

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Eliz, do you take these daily or just when you are having problems with leg cramps?

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Profile picture for sparklegram @sparklegram

@jeaniebean, thank you for your reply. I do take a daily supplement of Calcium, Magnesium, Zinc, Vitamin D3. 5 MCG of D3, 333 mg of calcium, magnesium oxide 133mg, zinc 5 mg. Is that enough magnesium?

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@sparklegram
Like others, I get occasional leg/foot cramps at night as well and I take 100mg of magnesium and 250mg of calcium citrate-malate, both twice a day for it. It seems to help.

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