Aromatase Inhibitors: Did you decide to go on them or not?

I totally sympathize! Because of the small keyboard I tend to always go to my desk top computer as much as possible.

Ah, the tiny telephone keyboard, lol. Thanks for trying and maybe you can post it later in full.

I tried but I kept losing it and having to redo it!

Sent from my iPhone

Maybe it's just me, but I'm reluctant to download and open a pdf to my devices. Can't you post your information as text?

See pdf below

Bisphosphonates help in preventing bone loss, to a degree, and resulting in less healthy bone interfering in the renewal cycle, but have a lot of unwelcome side effects or people on these and other threads, and studies, wouldn't be reporting them and warning against them. I have a friend who now has osteonecrosis from years of one of them and in terrible distress. I realize that not everyone wants to know about side effects so post as little about them as I can. But they are fully documented and medical fact and part of any story about a drug's benefits.. Prolia is a target of multple class action suits for failure to adequately report negative side effects. Just one example, several people have posted here, in the threads for osteoporosis, macular degeneration.

Merck knew about the cases of osteonecrosis caused by bisphonate, Fosamax, but tried to cover that up. (From disclosure in one of the many lawsuits about it, one of which includes my friend in its class. There is NO treatment for osteonecrosis, aka dead bone aka crystallized bone so damages will be of zero comfort. And unlikely to even cover the extensive dental and oral surgery costs.)

For those who want early information on drugs' negative side effects,, sometimes the best place to read, early, about side effects is in the financial press. Institutional investors ask really tough questions at security analysts' and shareholders' meetings and frequently have pharmaceutical consultants on staff. They are hard-nosed about seeing any bad side effect coming down the pike, more so, I think, than the FDA. N.B. My professional life includes participating in these investment forums and monitoring sales of company stock by inside management so I am speaking from first-hand experience.

Clearly Prolia and biphosphonates help in preventing bone loss when on aromatase inhibitors (though I did not go on them based on doc's concerns about other conditions). Clearly they are also helpful when dealing with recurrence/spread in terms of preventing pain and fractures. The remaining question is what role they might play in preventing recurrence or spread. If that was found to be true 20 years ago, that research would still be valid unless disproven! I have a copy of one study in a folder somewhere that was pretty convincing, but cannot find it online. I'll post it if I find it.

I agree about asking for the latest research. The range of available drugs for osteoporosis that a study comparing them, done, say 10 years ago, is of very limited vslue.

Can I ask why the glucose blocking? Is this related to sugar being kind of supporting of some breast cancers or something else? Sugar consumption is the bane of my existence, or at least diet, and I'm trying to eliminate it after seeing some studies relating it to breast cancer.

I started with Arimidex before surgery. No complications. Physician prescribed a drug for muscle spasms after surgery and I had huge SE. Moved to Letrozole. Could not stand, so dizzy. Looking back I felt so out of it. My husband travels all week, kids are at university so I just stumbled around trying to work from home. Going back to Arimidex every other day. The oncologist recommended it. Seeking out hormone and glucose blocking using other methods with a DO who specializes in cancer. Maybe Traditional Chinese Medicine too.
Hope that helps. Best to you.