1. < Neuropathy

Anyone try mexiletine for neuropathy?

Posted by zav @zav, Jan 14 10:30am

The latest suggestion from my neurologist. 150 mg per day with max 300 mg. Cleared by cardiologist because the drug has been traditionally used for heart issues.

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Mentor
John, Volunteer Mentor | @johnbishop | Jan 14 10:51am

Hi @zav, I think that @marenew and @jlor might have some experience or information on mexiletine. I did share these articles that mention the drug in another discussion and might provide more information on the drug and treatment.

— Neuropathic Pain: Principles of Diagnosis and Treatment:
https://www.mayoclinicproceedings.org/article/S0025-6196(15)00105-6/fulltext
— Office approach to small fiber neuropathy:
https://www.ccjm.org/content/85/10/801
— Small fiber neuropathy as a part of fibromyalgia or a separate diagnosis?
https://www.openaccessjournals.com/articles/small-fiber-neuropathy-as-a-part-of-fibromyalgia-or-a-separate-diagnosis-12822.html

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zav | @zav | Jan 14 2:04pm
In reply to @johnbishop "Hi @zav, I think that @marenew and @jlor might have some experience or information on mexiletine...." + (show)
@johnbishop

Hi @zav, I think that @marenew and @jlor might have some experience or information on mexiletine. I did share these articles that mention the drug in another discussion and might provide more information on the drug and treatment.

— Neuropathic Pain: Principles of Diagnosis and Treatment:
https://www.mayoclinicproceedings.org/article/S0025-6196(15)00105-6/fulltext
— Office approach to small fiber neuropathy:
https://www.ccjm.org/content/85/10/801
— Small fiber neuropathy as a part of fibromyalgia or a separate diagnosis?
https://www.openaccessjournals.com/articles/small-fiber-neuropathy-as-a-part-of-fibromyalgia-or-a-separate-diagnosis-12822.html

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Thanks John! This thing is becoming more of a nightmare, although the back issues could be a big part of it, but not really a good candidate for surgery, or so says the neuro-surgeon. It is getting more painful in the legs causing difficulty in walking, and tragically, the quality of life is deteriorating to the point that I don't seem to have the desire to undertake much; pain is wicked. I used to be something of a rebel! No longer. LOL. Again, thanks so much. Will try the drug and see if it helps. A pity about Cymbalta, but the b/p results on two attempts were just too high.

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