Anyone else finding immunotherapy a challenge?

Hi everyone- I am post surgery (11/3/25) for Squamous Cell EC- Stage 3. Did 6 rounds of chemo and 28 radiation prior to surgery....started immunotherapy in January. I am finding the impact of immunotherapy on my mood/ energy and the way I metabolize medications to be far greater than I expected. Namely- I feel REALLY down and "blah" for awhile after.
I can't determine if this is me trying to do too much when I was giving myself more of a break (or maybe it was that the world gave me more of a break?) when I was doing the chemo/radiation and at that point it was clear that I was going through something, but now that I am post surgery and back to my regular routines that it is assumed I am no longer going through a thing by the world around me?
I don't know. I only know this feels like a greater struggle than the chemo/radiation...