Anybody know anything about B7-H3 for treating prostate cancer?

Posted by johndavis60 @johndavis60, 1 day ago

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

heavyphil | @heavyphil | 8 hours ago

John, B7H3 is a surface protein very prevalent in aggressive PCa.
So far, there is no specific immunotherapy that targets it, but the literature calls it ‘promising’.
From a quick search there is a LOT of interest right now but I couldn’t find any ongoing clinical trials. Hope this helps.
Phil

johndavis60 | @johndavis60 | 8 hours ago

In reply to @heavyphil "John, B7H3 is a surface protein very prevalent in aggressive PCa. So far, there is no..." + (show)

Thanks Phil,
This might be the trial:
https://clinicaltrials.gov/study/NCT06551142

heavyphil | @heavyphil | 5 hours ago

In reply to @johndavis60 "Thanks Phil, This might be the trial: https://clinicaltrials.gov/study/NCT06551142" + (show)

GSK has received breakthrough approval for small cell lung, cancer and osteosarcoma. Don’t see why prostate cancer shouldn’t be next on the list since aggressive cases exhibit such high amounts of the surface protein.🤞