Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?

Posted by dedehans @dedehans, Aug 20, 2022

My close friend has had Pluvecto treatment suggested to him by oncologists. It is relatively new, having been approved by the FDA in March 2022. Have any of you been given this drug? I have read it is radioactive material and patient needs to stay away 6 ft from others for at least 3 days so as not to contaminate them. He has not yet decided whether to take the treatment or not as he is feeling awful enough as is.

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@whudup1

Has anyone done treatments with Pluvicto??

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My husband has had two treatments. While it appears to be helping him, I’m very concerned about the efficacy of this treatment.

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In reply to @whudup1 "Is this It?" + (show)
@whudup1

Is this It?

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That seems to be it. I didn't see the packaging.
Day after the treatment I had some stomach issues. diarrhea included. Extremely tired, which is normal lately, so I don't know if it is related to the Pluvicto.
My stomach seems more settled today, but I am still very tired.

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I meant to say "now scheduled" in my previous post. Amazing what a single letter can change.
Pluvicto treatment went fine. Technically, no different from the IV Chemo, but I didn't feel as terrible after.
My night last night was no better nor worse than any other recent night, which is good since the IV Chemo for me was horrible. I missed my wife, who slept in a different room per radiation protocol, but I suppose she didn't miss my snoring...
I don't feel badly this morning. Perhaps it is just too soon to see any side effects.
I am hopeful that this will help. The techs told me of a previous guy who needed a catheter to urinate. I'm not at that point, but close enough to empathize. Anyway, just his first Pluvicto treatment allowed him to stop that and go back to normal urination.
On the less good news report, the attending Dr tells me that Pluvicto treatments statistically give us about four months more lifespan than the control group.
Hey, I'll report more later, but hopefully it is as boring as this one.
To all you who suffer from this, and to all your caretakers, my heart goes out to you and may God bless each of you.

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The supply problem with Pluvicto is a real issue. I was scheduled twice and cancelled both times. I am not scheduled for my first dosage on Monday, 4/17/23. I'll keep y'all posted on how I do with it. This site has the most comprehensive information on the Pluvicto that I could find, so thanks for that.
BTW, I am being treated at MD Anderson in Houston.
I'll post again in a few days...

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@whudup1

Has anyone done treatments with Pluvicto??

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@whudup1, I moved your question about Pluvicto to this active discussion:
- Anyone on Pluvicto (Lu 177), a new drug for prostate cancer? https://connect.mayoclinic.org/discussion/any-one-on-pluvecto-a-relatively-new-drug/

I encourage you to read previous posts and connect with others like @dlylecpa @robert570 @donalan @leebeth @bamaples @hpete710 and others who have experience with this treatment.

@whudup1, is Pluvicto an option for you?

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Has anyone done treatments with Pluvicto??

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I received my 1st Pluvicto Treatment on March 17. The only side effects I had, was a dry mouth the first week. That is mostly light now. I was pretty normal the first week with minimal side effects. This week I am very weak, sore and stiff. My jaw was aching, but I believe it was my sinuses, which Ohio is famous for. Could be from the Pluvicto, but it's not setting me back that much. I have a strong appetite and I'm feeling better as of today. My biggest complaint is fatigue.

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@dmrice

Where is he getting treatments Pluvicto is almost impossible to get. How many treatments do the drs believe he should get?

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My husband gets them in Arkansas. He has been on a list for about 9 months. He's supposed to get 6 treaments.

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