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Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?
My close friend has had Pluvecto treatment suggested to him by oncologists. It is relatively new, having been approved by the FDA in March 2022. Have any of you been given this drug? I have read it is radioactive material and patient needs to stay away 6 ft from others for at least 3 days so as not to contaminate them. He has not yet decided whether to take the treatment or not as he is feeling awful enough as is.
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Had my second treatment of Pluvicto on Monday. Typical IV treatment and that was all good until my claustrophobia kicked in while they did the scans three hours after.
So I am about 36 hours after and this one hit me harder than the first. The fatigue is monumental. I'm exhausted, but long ago decided to just sleep through these bouts of extreme tiredness. Which is what I've been doing since the treatment.
Some less genteel details: Urination has not really changed, but I didn't expect any changes in this time frame. There is improvement since the first treatment, though not as much as I hoped. I seem to be dealing with constipation also, which is the opposite of what I noticed the first time around.
Since it is only my wife and I (bless her caregiving heart), we don't have much issue with staying six feet apart. We do have a new kitten and I've been staying away from him, but the treatment notes say I can pick him up and hug him and hold him and squeeze him starting tomorrow at noon.
Round two. I'll keep posting as my treatment continues or I have other symptoms from this round.
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3 ReactionsI did get my supply from Italy, according to the Dr who administered the Pluvicto. My six treatments are now scheduled out through November at about six week intervals.
I am at seven days after the IV. My first week I was very, very tired. No energy and no interests. Had some stomach issues the first few days, but that leveled out. I can urinate better now than immediately before treatment, so that’s a plus.
FYI, I still have my prostate. My previous Dr did a TURP on me instead of removing the prostate. The TURP is ultimately failing. I guess I heal internally, but I think it was a bad call considering all the issues I have with urination and BM lately. TMI?
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1 ReactionHi sounds good,I heard pluvicto was hard o get that there is a shortage of it I think will be headed to that soon there making a place in N Jersey to make it,but won’t have fda approval till July it comes from Italy
My husband has had two treatments. While it appears to be helping him, I’m very concerned about the efficacy of this treatment.
That seems to be it. I didn't see the packaging.
Day after the treatment I had some stomach issues. diarrhea included. Extremely tired, which is normal lately, so I don't know if it is related to the Pluvicto.
My stomach seems more settled today, but I am still very tired.
Is this It?
https://seer.cancer.gov/statfacts/html/prost.html You can separate by age, race etc
I meant to say "now scheduled" in my previous post. Amazing what a single letter can change.
Pluvicto treatment went fine. Technically, no different from the IV Chemo, but I didn't feel as terrible after.
My night last night was no better nor worse than any other recent night, which is good since the IV Chemo for me was horrible. I missed my wife, who slept in a different room per radiation protocol, but I suppose she didn't miss my snoring...
I don't feel badly this morning. Perhaps it is just too soon to see any side effects.
I am hopeful that this will help. The techs told me of a previous guy who needed a catheter to urinate. I'm not at that point, but close enough to empathize. Anyway, just his first Pluvicto treatment allowed him to stop that and go back to normal urination.
On the less good news report, the attending Dr tells me that Pluvicto treatments statistically give us about four months more lifespan than the control group.
Hey, I'll report more later, but hopefully it is as boring as this one.
To all you who suffer from this, and to all your caretakers, my heart goes out to you and may God bless each of you.
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2 ReactionsThe supply problem with Pluvicto is a real issue. I was scheduled twice and cancelled both times. I am not scheduled for my first dosage on Monday, 4/17/23. I'll keep y'all posted on how I do with it. This site has the most comprehensive information on the Pluvicto that I could find, so thanks for that.
BTW, I am being treated at MD Anderson in Houston.
I'll post again in a few days...
@whudup1, I moved your question about Pluvicto to this active discussion:
- Anyone on Pluvicto (Lu 177), a new drug for prostate cancer? https://connect.mayoclinic.org/discussion/any-one-on-pluvecto-a-relatively-new-drug/
I encourage you to read previous posts and connect with others like @dlylecpa @robert570 @donalan @leebeth @bamaples @hpete710 and others who have experience with this treatment.
@whudup1, is Pluvicto an option for you?