Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?

Thank you to all. He has tried a number of mints / candies with and without xylitol, sprays, washes, nothing seems to help. We are more interested in..,.if you had Pluvicto and lost all saliva - did it ever return (saliva) or once its gone is it gone forever. Can't seem to find a study that says and doctors/techs don't seem to know either, THANK you

Xylimelts XyliMelts Adhering Pastilles Mild Mint Falvour at CVS XYILOMELTS

Hard candy or mints with xylitol help. Haven't tried the Biotin yet but it was also recommended at Mayo Rochester.

Bye https://smartmouth.com/blog/xylitol-mi…
https://smartmouth.com/blog/xylitol-mints-dry-mouth/
XylitolMints Help Relieve Dry Mouth - Smart Mouthtabs at drug store 2 for one Put in mouth at night

Colgate makes a dry moth tooth past Then biotin

My husband completed his Pluvicto 2 months ago. The dry mouth is still severe. Has anyone had the saliva return?

My husband completed his Pluvicto 2 months ago. The dry mouth is still severe. Has anyone had the saliva return?

Pretty much the same thing is happening to me....after the second Pluvicto injection, I was having a much harder time recovering from fatigue, malaise, loss of appetite and difficulties evacuating . My PSA had risen from 17 to 24, that's the highest jump I have had so far in my four years battle.My oncologist immediately schedule for a bone and upper body scan to see if more metastatis has occured. I am doing the scans tomorrow ( 2-26 ) . Depending on the results, he will evaluate weather to continue on with Pluvicto or not. I am glad i found your post and others. It is possible that the PSA my lower and rise indipendently from other factors I guess. The only sure way to determine progression lays in imaging.... a bit nervous about tomorrow, but I hoping the results will be ok. Thanks.

My PSA also rose after two treatments. My oncologist and I decided the Pluvicto was not working and cancelled further treatments. Two weeks later my PSA plummeted from 37.6 to 7.2 and then three days later to 5.4

We're back on the Pluvicto treatment schedule.

I will say that the second dose caused me much major discomfort in my GI tract. My bowels and bladder were hard to empty for days. Managed to get past it, but I did think I was finished at that point. Depression, as we all know, is too real now.

My best wishes and prayers to all my comrades out there and their caretakers.