Any hope for aggressive metastatic prostate cancer?

Posted by jojoteacher18 @jojoteacher18, Apr 21, 2023

My husband, 60, just got an MRI report that stated aggressive metastatic prostate carcinoma >15 that spread to bladder and anus walls. We have an appointment with the urologist in 3 days. This feels so hopeless. Symptoms have been difficulty urinating mostly. PSA ranging 5-7 over the past month. IS THERE HOPE?

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@hairbrain

Thank you for responding, my oncologist informed me yesterday that I have months left. I am still positive, refusing to take hormone therapies, been through enough. The side effects do not warrant living longer to be miserable. My CML is in remission thanks to the generosity of Novartis and their Tasigna.

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Stop it

Get on Zolodex injections every 3 mos 2 yrs later now added Xtandi or Enzulutimide 4 easy swallow pills a day Just added Xgeva injections to move calcium into bones

It works No big side effects Tired a bit but this side of the grass for 5 more plus they say then other plans 78

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@m49p

This gave me hope today. Thank you.

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They say that “hope lives eternal”!! For those of us battling this disease, many for years, this is our mantra!
May God bless and care for us all!

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@colleenyoung

@hairbrain, what treatment options for prostate cancer are being suggested now? Are you also getting treatment for CML or active surveillance?

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Thank you for responding, my oncologist informed me yesterday that I have months left. I am still positive, refusing to take hormone therapies, been through enough. The side effects do not warrant living longer to be miserable. My CML is in remission thanks to the generosity of Novartis and their Tasigna.

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@hairbrain

Thank you, have been dealing with prostate cancer for seventeen years. Treated with HIFU, surgery and radiation, cancer returning after each. Received the bonus of CML after radiation and stage IV prostate cancer one year after getting it in remission. It has been a journey.

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@hairbrain, what treatment options for prostate cancer are being suggested now? Are you also getting treatment for CML or active surveillance?

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After 3 yrs it met to L2 spine Had it radiated and put on Zolodex injections every 3 mos 2 yrs later now added Xtandi or Enzulutimide 4 easy swallow pills a day Just added Xgeva injections to move calcium into bones

Its working Look into it and targeted radiation

also study https://seer.cancer.gov/statistics-network/explorer/application.html?site=66&data_type=1&graph_type=2&compareBy=stage&chk_stage_106=106&hdn_rate_type=1&hdn_sex=2&race=1&age_range=166&advopt_precision=1&advopt_show_ci=on&hdn_view=0&advopt_show_apc=on&advopt_display=2#resultsRegion0

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I had aggressive prostate cancer show up in July I was already on hermonal therapy psa was .04 they put me on chemotherapy it that’s probably what is coming good luck 🙏

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@cshap


This is a good zoom video from Dr Nazzi, talks about ivm and docetaxel at the 19 min mark

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Thanks for finding and posting this video with Dr. Lucia Nappi, senior research scientist at the Vancouver Prostate Centre and a clinician scientist medical oncologist.

She does a good job of explaining preclinical studies and the process of human studies from phase I to III (and there's also a phase IV). She speaks of several new approaches currently in laboratory and mice trials, and early human trials that offer hope for future treatment options.

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@hbp

A 17 year journey is indeed a successful one but not one without its substantial burdens. It is a journey worth doing. Keep on fighting man!!

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Amen!

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Michael Milken is a cancer survivor of over 20 years. See this article.
https://gwtoday.gwu.edu/mike-milken-i-can-see-end-cancer-cause-death
That was 1990 that he was diagnosed and given 2 years to live. He beat it with diet and what was available medically.
I had prostate cancer in 2021 WITHOUT metastasis and am in remission now for the last 1.5 years.
I believe that much like Milken you and I have a much better chance by changing lifestyle. Exercise, sleep, fasting, diet, cold plunges. I suggest reading How Not to Die by Dr. Greger and the work by David Sinclair
https://healthnews.com/longevity/healthspan/david-sinclair-diet-and-key-principles-for-longevity/
Reading Rhonda Patrick (another research scientist) you will find that exercise can shunt away energy from cancer cells. Cancer thrives on glucose - (Read Dr Attia's book Outlive). Fasting and exercise can deprive it of that glucose and allow your body's immune system to possibly kill it.
My personal anecdata is that as someone that regularly got skin cancer (basil cell carcinoma) and had it surgically removed, I got what appeared to me and my dermatologist to be another case of it and the area around it became red (inflammed) and he said let's wait until that calms down ... and then it went away. This is after I had been on Greger's diet, was fasting daily (8 hour eating window) and exercising while in a fasted state. Also taking hot baths followed by cold showers (go to Hubermanlab.com and listen to the interview with Rhonda for a protocol). Anyway I hope to stay in remission and am doing all I can to stay healthy. Wish all of you (and me ) the best.

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@hairbrain

Have stage IV prostate cancer, no insurance, scans last week demonstrated innumerable sclerotic foci lesions on my pelvis, spine and chest along with compression fractures of T8-T10. Seeing my oncologist next Tuesday. Feel like I am dying. Any hope or should I ride this out.

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Never lose hope. It’s not an option. There is treatment for your specific case. My concern is the lack of insurance bc this drugs are quite expensive. See what your oncologist offers as treatment and look forward to getting better. I will be praying for you and your family and please DO NOT LOSE HOPE.

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