Any good results with anti-psychotic medication for dementia?

Posted by robertwills @robertwills, Jul 10 2:03pm

Anti-psychotic medication nearly completely reversed mana in patient, 85 years old. Now patient is having mania again but not nearly as bad. Neurologist says it's Alzheimer's and the disease has simply progressed. No change in medication. Could this diagnosis be wrong? Could patient simply need a higher dose of the medicine that initially worked?

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I think a little more information would give better insight...ie what was her behavior before starting on the
anti-psychotic medication and which one? And currently, what are her behaviors. Is she at home with family or in a facility and have other treatments been attempted?

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Started with mild dementia. Could converse like they had all their life, drive a car, go shopping, etc.. Then within 2 or so weeks of having a simple outpatient procedure (maybe with anesthesia) went fast into full blown mania with crying, anxiousness, discomfort, not sleeping for days, became 500% more frail. Within days after the anti-psychotic medication (given about 3 weeks after mania started) symptoms mostly went away and patient was 90% like normal. Now over a year later having mania again but not as severe.

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Every time my cousin had anesthesia for surgery she went through a month or two of crying, depressiion. But this was maybe beginning of her dementia. Two years ago her dementia required her to go to memory care facility. She was doing dangerous things, taking too much prescribed medication, unplugging her phone, and many other difficult behaviors.

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@robertwills

Started with mild dementia. Could converse like they had all their life, drive a car, go shopping, etc.. Then within 2 or so weeks of having a simple outpatient procedure (maybe with anesthesia) went fast into full blown mania with crying, anxiousness, discomfort, not sleeping for days, became 500% more frail. Within days after the anti-psychotic medication (given about 3 weeks after mania started) symptoms mostly went away and patient was 90% like normal. Now over a year later having mania again but not as severe.

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I feel elders have a difficult time post-anesthesia, perhaps age is not factored in with administration of drugs. Could this person benefit from a dosage adjustment? .....rather than starting a new drug as each drug carries with it different side effects. If they have done well on this particular anti-psychotic then a dosage change might be better. Just my opinion.

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@kndaustin71

I feel elders have a difficult time post-anesthesia, perhaps age is not factored in with administration of drugs. Could this person benefit from a dosage adjustment? .....rather than starting a new drug as each drug carries with it different side effects. If they have done well on this particular anti-psychotic then a dosage change might be better. Just my opinion.

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The doctor may increase the dosage of the antipsychotic medication if the condition does not get better. How long this will be I do not know. I do know that it initially took weeks to even give them something that worked. No one is saying anything about the procedure right before the decent into mania. I believe it should be looked into more before just saying it's progressing Alzheimers.

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@robertwills

The doctor may increase the dosage of the antipsychotic medication if the condition does not get better. How long this will be I do not know. I do know that it initially took weeks to even give them something that worked. No one is saying anything about the procedure right before the decent into mania. I believe it should be looked into more before just saying it's progressing Alzheimers.

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If the physician does increase the dose, perhaps they might try using a short-acting as needed medication until the new dosage has time to be effective. I do feel that people who are manic and have behaviors are very uncomfortable and need relief of some sort. It's really trial and error but the goal would be not to over-medicate to a degree that it alters their activities of life. Anti-psychotic medication tends to be sedating if not careful.

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