Anastrozole fatigue - what helps?

Posted by flowergal @flowergal, Apr 22, 2024

I'm having a tough time staying alert/ awake in the afternoon since I started this drug.
I'm using energy patches, drinking electrolytes but I still crash and have to lie down and I fall into deep sleep.
Hard to get much done. Any thoughts?

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I found cancer treatment in general to be tiring--surgery and radiation in particular. Letrozole seems to have had no negative effects over 18 months. However, my approach to mid-afternoon fatigue is to lie down and take a nap! It really works and gives me a second wind. I've had fatigue my entire life, since a severe illness at age 21 that resulted in some disability. When I was working full time I had a futon folded under my desk and would have a quick lie-down in my office. Not every work place is conducive to that (I have a family member who took power naps in his parked car when working as a tech writer for aerospace manuals!). Basically if your time is your own, take a rest. And post cancer treatment you might be able to get an accommodation at work. I find our society doesn't seem to value rest, but truly it is very healing. You can also ask your doctor for a break from AI to see if that works. However, it took me at least six months post surgery/radiation to feel less tired. Thinking of you and hoping you feel energy return.

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I'm on Exemestane and have the same struggle. Going to follow this thread as I would love tips too. I feel a hit the wall feeling between 1-2pm everyday. I am going to ask my Onc about a high dose of Vit D but dont have apt for a few weeks.

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