Aromatase Inhibitors: How to choose and manage side effects?

Posted by shebell @shebell, Sep 11, 2024

I was diagnosed in April 2024 stage 1 invasive ductal carcinoma - estrogen positive. I had lumpectomy and radiation my onco score was 12 so was able to skip chemo therapy. I have tried Anastrozole and had terrible side effects I have not tried Tamoxifen yet and am seriously thinking about forgoing any AI long term treatment has anyone else made that choice?

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I switched to letrozole then switched manufacturers then did brand name. In the end, I did find a generic that I could tolerate. There are things you can try....switching meds, manufacturer or doing brand name.

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Thank you Laurie! I will check additional sites. I have talked with my oncologist and we are exploring other drug options. They all have such daunting side effects. I am turning 60 this year and a very active runner and weight lifter with no prior health issues so the medication struggles are a new journey for me and certainly not one for the faint of heart🥴

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@shebell,

You might want to check out the following similar discussion:
Stopping AI and Starting Tamoxifen
https://connect.mayoclinic.org/discussion/stopping-ai-and-starting-tamoxifen/
Stop the Madness (stopped taking my AIs)
https://connect.mayoclinic.org/discussion/stop-the-madness/
I tried AIs and Tamoxifen and after serious discussion with provider and my recurrence rate, I decided to take the risk. I also had chemo, which reduced the recurrence rate.

Have you discussed the side effects or not taking any medications with your oncologist?

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