Advanced Prostate Cancer

Posted by stackthewood @stackthewood, Feb 27, 2023

I had prostatectomy in 2008. In October 2022, my PSA was 82.0. A second PSA test was 89.0. Then, I had a PSMA/PET Scan. This Scan showed the prostate cancer had spread to various parts of my body. The cancer had been detected in my neck, my chest, my abdomen, my pelvis, and my lower spine. It was classified as Advanced Prostate Cancer. My doctor ordered the injection of Lupron every 3 months. I had the first injection in early January 2023. Also, he prescribed Erleada (Apalutamide). I take four 60 mg tablets every day. I have taken these tablets for about one month. About 10 days ago, I had another PSA test. This time my PSA was 0.81! Is that possible for the PSA to drop 99%? My doctor says I will continue to have the injections and continue on the medication. Please advise. Thank you.

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vjlvpjalways | @vjlvpjalways | Feb 28, 2023

Yes it’s doing it’s job..next text hopefully your at 0 or >less than the labs ability to register..the Lupron stops your body from making testosterone and starves the prostrate cancer so it’s not able to produce PSA.. Hopefully you remain PSA sensitive many many years.. I am currently set to receive third Lupron in 2weeks..

narus | @narus | Feb 28, 2023

In reply to @vjlvpjalways "Yes it’s doing it’s job..next text hopefully your at 0 or >less than the labs ability..." + (show)

There are new alternatives to Lupron, Relugolix is new and a good option.

melcanada | @melcanada | Feb 28, 2023

In reply to @narus "There are new alternatives to Lupron, Relugolix is new and a good option." + (show)

After 2 years zolodex they added xtandi or enzymes 4k a month covered expect it to work average 18 most then something else

Psa back down fast

78 and appreciate life each day

narus | @narus | Feb 28, 2023

I have not been in your position my PSA was 4.19 then without treatment at all it went down to 3.
I was on Lupron for six months and it ruined my life for a year. I am on testosterone therapy about a year, lost 40 pounds and feel great.
I am 65 and if I had to go back on Lupron I would start looking for nursing homes. It severely degraded my quality of life.

spryguy | @spryguy | Feb 28, 2023

In Mar of 2022 my PSA was 83.4. Lupron 6 mos injection. 39 sessions of IMRT that ended July of 2022. Sept 2022 PSA was 0.8 Oct. Added Zytiga.
Oct 2022 PSA was now undetectable (