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3263 Trial for PanCan

Posted by howleegirl @howleegirl, 6 days ago

Is anyone on this trial? What kind of side effects are you having? How long are they lasting?

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mcharlesfrancis | @mcharlesfrancis | 6 days ago

At this point, ALTA3263 is still in Phase 1 testing, so there is very limited human side-effect data publicly available. The trial's primary purpose is to determine safety, tolerability, and dosing.

Based on experience with other KRAS inhibitors, oncologists will likely be watching closely for:

Diarrhea
Nausea
Fatigue
Rash or skin changes
Elevated liver enzymes
Decreased appetite
Blood count abnormalities

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howleegirl | @howleegirl | 6 days ago
In reply to @mcharlesfrancis "At this point, ALTA3263 is still in Phase 1 testing, so there is very limited human..." + (show)
Profile picture for mcharlesfrancis @mcharlesfrancis

At this point, ALTA3263 is still in Phase 1 testing, so there is very limited human side-effect data publicly available. The trial's primary purpose is to determine safety, tolerability, and dosing.

Based on experience with other KRAS inhibitors, oncologists will likely be watching closely for:

Diarrhea
Nausea
Fatigue
Rash or skin changes
Elevated liver enzymes
Decreased appetite
Blood count abnormalities

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@mcharlesfrancis I believe it is in late stage 1 testing. They started my husband on 300mg 2x a day. He's only been on it 5 days and has started to get occasional diarrhea, nausea, and fatigue. All seem to be controllable.

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