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putting dental implants when you have osteoporosis

Osteoporosis & Bone Health | Last Active: Jan 21 2:01pm | Replies (31)
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@surefire

Thank you for the CTX table - it is very helpful. But this is what's puzzling me and I hope someone can enlighten me.

I have read that high CTX numbers imply high bone turnover and higher fracture risk. Anti-resorptives like Fosamax have the effect of slowing bone turnover leading to lower CTX numbers. It was in fact proposed in a PubMed article that the lower half of the premenopausal range be set as a target for treatment i.e. 50-190 pg/ml for CTX. So I had been under the impression that low CTX numbers are something to aim for. But judging from your table, it seems that the lower the CTX numbers, the higher the risk of ONJ. Am I missing something?

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Replies to "Thank you for the CTX table - it is very helpful. But this is what's puzzling..."
kristie2 | @kristie2 | Jan 19 9:59am

Per McCormick he said that the preferred range is 200-300 range.
I understand your concerns .

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mayblin | @mayblin | Jan 19 3:53pm

I'm reading bone markers related information these days...

Can it be interpreted this way: when a person is treated with an antiresorptive, both CTX and P1NP are suppressed. CTX is the one usually used for antiresorptive therapy monitoring. So when it is extremely low, below 150 worse yet below 100, there are little chances to form new bones hence little chance for healing. Normally one would need CTX and P1Np at certain level for bone remodeling.

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