I completed 12 shots of evenity in December. I had excellent results, especially in my spine where my bone density increased by 15%. I always drink a lot of water before I got the shot and I kept a bottle of water in my car for the drive home. I usually got a slight headache afterwards, which was alleviated with a couple of Tylenol. I might have had the side effect of making my arthritic hands a bit more painful but I am not certain I can attribute that to the evenity