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Rash/Hives with Octreotide injection

Posted by katinka58 @katinka58, Jan 7 8:21pm

My husband has taken the Octreotide injection now for about 2.5 years. This past summer he started breaking into a rash/hives on the face & neck, looking like a horrible bout of acne. We asked the oncologist & he said has never seen this, he uses Benadryl which kind of calms the itch; he has also tried cortisone cream ….. He changed razors & has changed strictly to oatmeal bar soaps . Has anyone else been through this .

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ahtaylor | @ahtaylor | Jan 9 6:44pm

Thanks for your post! I thought I might be the only one with reactions to octreotide! I took lanreotide first and developed rash, hives and some respiratory symptoms. I was off the medication for 2 months and then switched to Sandostatin/octreotide. I did well with the first dose. I developed rash/hives with the 2nd dose which persisted. On dose #4 I developed chest pain within 10 minutes of the dose which was eventually ruled to be an allergic reaction. With dose #5, I was pre-treated with steroids and 8 hours post-injection had an anaphylactic reaction. We stopped the octreotide for 10 months until the hypoglycemia became so severe (I have insulinomas) that I needed the benefits of the medication. In Dec 2022, I did a desensitization to octreotide and have been on it since. I still have some reaction to the medication but not anaphylaxis. I work with an allergist closely to provide anti-allergy regimens that help keep reactions under control. Best wishes in your journey!

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1 reply
Moderator
Colleen Young, Connect Director | @colleenyoung | Jan 14 9:51pm

@katinka58, I hope you saw the helpful post from @ahtaylor. Your husband is not alone.

How is he doing?

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1 reply
katinka58 | @katinka58 | Jan 14 10:01pm
In reply to @colleenyoung "@katinka58, I hope you saw the helpful post from @ahtaylor. Your husband is not alone. How..." + (show)
@colleenyoung

@katinka58, I hope you saw the helpful post from @ahtaylor. Your husband is not alone.

How is he doing?

Jump to this post

The rash is clearing up slowly, some months he gets it worse. He hurts as well as he has also been diagnosed with bone cancer this just sucks !!! Thank you

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vinnie694 | @vinnie694 | Jan 15 10:50am
In reply to @ahtaylor "Thanks for your post! I thought I might be the only one with reactions to octreotide!..." + (show)
@ahtaylor

Thanks for your post! I thought I might be the only one with reactions to octreotide! I took lanreotide first and developed rash, hives and some respiratory symptoms. I was off the medication for 2 months and then switched to Sandostatin/octreotide. I did well with the first dose. I developed rash/hives with the 2nd dose which persisted. On dose #4 I developed chest pain within 10 minutes of the dose which was eventually ruled to be an allergic reaction. With dose #5, I was pre-treated with steroids and 8 hours post-injection had an anaphylactic reaction. We stopped the octreotide for 10 months until the hypoglycemia became so severe (I have insulinomas) that I needed the benefits of the medication. In Dec 2022, I did a desensitization to octreotide and have been on it since. I still have some reaction to the medication but not anaphylaxis. I work with an allergist closely to provide anti-allergy regimens that help keep reactions under control. Best wishes in your journey!

Jump to this post

I have to take Benadryl prior to my injections to prevent a respiratory reaction, my first shot I was in the emergency room within 30 minutes of receiving the injections…

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