An interplay occurs among stomach acids, cough and sinuses for sure! Once I elevated the bed high enough and eliminated eating/drinking (and chocolate, so sad) 3 hours before bed, I've been better. Reflux is known to exacerbate sinus and lung disease when unchecked.

With bronchiectasis our job is to clear the accumulated mucus. My suspicion is that mucolytics draw extra fluid out of the mucin/mucus layer *along with* the bronchiectasis mucus. But we only need to clear the accumulated bronchiectasis mucus. Albuterol and 7% saline help us do this without impacting the mucin/mucus layers. I believe this is why my chest rumbled at night because the mucinex NAC was still busy drawing fluid out of the mucin/mucus layer(s). Dunno for sure but happy to be getting more sleep.