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@gently

roger, when you first begin steroid use bone loss is caused by an increase in osteoclasts. With long term use steroids reduce the number and the life span of osteoblasts. Reducing the dosage of steroids, would lessen the effect, but may be detrimental to your breathing. Alendronate will address the osteoclasts; it doesn't build bone. It allows your body to preserve the bone you have. I don't know your numbers, but think you would be better served by a drug that addresses both aspects of bone quality building bone and reducing loss. Both Forteo and Tymlos are drugs you might ask your physician to consider.

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Replies to "roger, when you first begin steroid use bone loss is caused by an increase in osteoclasts...."

Here are my test results. Any ideas now?

BONE DENSITOMETRY (DEXA)

CLINICAL: Screening for osteoporosis. History of prior
fractures. History of long term steroid medication use for
treatment of asthma.

PROCEDURE: Bone densitometry, Standard.

BONE DENSITY:
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Region BMD T-score Z-score Classification
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AP Spine(L3, L4) 0.743 -3.5 -2.3 Osteoporosis
Femoral Neck (Left) 0.533 -2.9 -1.4 Osteoporosis
Total Hip (Left) 0.638 -2.6 -1.5 Osteoporosis
Femoral Neck (Right) 0.461 -3.4 -1.9 Osteoporosis
Total Hip (Right) 0.565 -3.1 -2.0 Osteoporosis
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10-year Fracture Risk:
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FRAX not reported because:
Some T-score for Spine Total or Hip Total or Femoral Neck at
or below -2.5
-----------------------------------------------------------------

My test results are attached to another comment. Any change or addition to what you wrote?