Thats a great question. I have used Plaxovid on 2 occasions, both for covid of course, which all it is currently offered for. I took it for the full 5 day course of treatment but frankly felt like new after onlyt one day on the med, both times.

To your question, however, I did learn that the original paxlovid could cause mild kidney issues in some patients. Since then they do provide a newer, kidney friendly version of the drug which I did receive 2nd time, which was about 4 months ago. I frankly don't know if original version is still available or not. I have had no kidney issues from my taking original dose. Obviously if this drug is ever put through trials for arthritis etc. it would be an altered version of current med, at least I would suspect!