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putting dental implants when you have osteoporosis

Osteoporosis & Bone Health | Last Active: Jan 21 2:01pm | Replies (31)
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@kristie2

I found this information on a endodontist Laboratory Risk Assessment for Patients taking oral bisphosphonates

CTX Value Risk for ONJ
300 to 600 pg/ml (normal) none
150 to 299 pg/ml none to minimal
101 to 149 pg/ml moderate
Less than 100 pg/ml high
They do a CTX valuation.

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Replies to "I found this information on a endodontist Laboratory Risk Assessment for Patients taking oral bisphosphonates CTX..."
tilou | @tilou | Jan 12 12:28pm

I dont take bisphosphonates and dont plan to take any anymore after a bad experience. Nevertherless thank you for your input.

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surefire | @surefire | Jan 19 12:43am

Thank you for the CTX table - it is very helpful. But this is what's puzzling me and I hope someone can enlighten me.

I have read that high CTX numbers imply high bone turnover and higher fracture risk. Anti-resorptives like Fosamax have the effect of slowing bone turnover leading to lower CTX numbers. It was in fact proposed in a PubMed article that the lower half of the premenopausal range be set as a target for treatment i.e. 50-190 pg/ml for CTX. So I had been under the impression that low CTX numbers are something to aim for. But judging from your table, it seems that the lower the CTX numbers, the higher the risk of ONJ. Am I missing something?

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