I have been to both Mayo AZ and Mayo Mn and there is no comparison. Mayo AZ is like your typical high quality large hospital while Mayo MN is a Medical City unto itself employing 35K+ people. Not knocking AZ since I'm going there and I am very pleased with my treatment but if I had a problem where my local MD's/hospitals are baffled, Mayo MN would be my very first choice. Yes, it's probably easier for you to get to AZ vs MN as it is for me. That's why I chose AZ for my continued care of one problem I have and again I am very satisfied with the care they offer. Please note that Mayo AZ DOES NOT ACCEPT ANY ADVANTAGE PLANS while Mayo MN does accept some. If she is on an Advantage Plan I would call Mayo MN first. Best of luck