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@livedinrochester

Wow. I am glad I just joined this. I did not really think anyone would respond. Thanks beesmom. Nice to know that I am not alone. I was always "blue" as a kid and later in life felt depression and anxiety too along with my Mom. I finally started ( I did not want something messing with my brain!) on Lexapro but just gained weight. Then Bupropion but could not handle the extreme dry mouth at night. Stopped that too and no dry mouth anymore. On nothing now but I probably should try something again. Do Zoloft and Trazadone work for you?

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Replies to "Wow. I am glad I just joined this. I did not really think anyone would respond...."

I also am a DES daughter, born in 1953. I had an abnormal Pap test while I was on birth control in my 20s. That led to research into the possible DES exposure. My mother had a couple of miscarriages. I stopped oral birth control then and never went back and Pap tests became normal. I did have a benign growth on one ovary and ovariectomy. I struggled with infertility but we were blessed with 3 beautiful children. I was treated for incompetent cervix with each pregnancy and was lucky to carry each baby to full term. Currently at 70 I have had metastatic Squamous Cell Carcinoma for 12 years. Numerous surgeries and radiation and now immunotherapy have me clear for the moment. I also have had hot flashes for 25 years but those are tolerable.
And as a side note, I have been a veterinarian for over 40 years and we have always had access to DES for canine incontinence. The dose used is miniscule compared to what pregnant women were given. In all my years I have never seen cancer or bone marrow issues in the treated dogs that was related to their intermittent DES treatment.

Yes, the Zoloft & Trazadone have worked. It’s not perfect. Still have the underlying anxiety that never lets me completely relax, but this combination has helped more than others. Wishing you the best!!!