Thank you @windyshores. It must have been in Great Bones where I read about Tymlos after Forteo. And thank you for sharing the study. I agree that it's very hopeful, though the combined treatment shown to be the most effective, would be incredibly expensive. Can you imagine what the side-effects could be when taking both at the same time?
In the Interpretation of that study it states, "In postmenopausal osteoporotic women switching from teriparatide to denosumab, BMD continued to increase whereas switching from denosumab to teriparatide results in progressive or transient bone loss."
For anyone who doesn't know about it, or is interested in learning more, this randomized control trial is cited and further explained in the recorded presentation that Dr. Benjamin Leder gave at the Cleveland Clinic about a year ago. The recording which is often referenced in this support group, is titled "Combined and Sequential Approaches to Osteoporosis Therapy". It can be viewed on YouTube.
Here's the link: https://youtu.be/WXoz1NeUgg8?si=Ka8vNnzsjDc9TZXA
It's a bit technical in parts, but well explained and very informative.
Thanks for sharing the video. I literally had to watch it in parts because i got so upset. If this is correct, I am really a lost cause. I am 56. I have been on prolia at least 4 years. I still have 3 months before another prolia injection and now the new supposedly "osteo" dr has put me on tymlos, which is reversed sequence. In 3 months she does not want to renew the prolia. Her plan is for me to stay on tymlos 18 mo then back to the prolia. I am so worried. I feel like I am doomed. I really don't know what direction to go. Prior to 3 months ago, I was extremely athletic, hiking, running, walking, and biking around 200 miles a week. Now I can only do short walks or hikes and strength training exercises.