1 node positive with RP followed by BCR after 3years

Posted by rkurtzjr @rkurtzjr, Jan 10 12:33pm

Anybody out there with similar situation? If so, what was your new treatment plan and how did it go?

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I had BCR in a matter of months...nodes clear, margins clear, but Perineural invasion was identified. A PSMA PET scan prior to radiation didn't reveal any cancer.
New Treatment was 39 radiation sessions and ADT meds (orgovyx for 2 years, still on it for another 5 mos)
Treatment was a PITA but it goes by fairly quickly. I had a couple bouts of the runs but not sure if that can be attributed to the treatment or life in general. The orgovyx comes with some side effects, different and different intensities for most people. Fatigue, (is that the drug or my age...) stiff joints (ditto), hot flashes, that's definitely the drug. After taking the drug for about 9 mos, the side effects either diminished some or I just got used to them. Won't really know till I stop taking it and start producing nature testosterone again.

PSA down to < 0.006 since 11/28/2022 (knock on wood, fingers crossed, scratch a stay, turn three times...etc. etc.)

movie reference ? anyone? LOL

Best of Luck to you!

REPLY

Not really enough information.
Have you been diagnosed with BCR?
See:
SPPORT trial

PCF.org video Jan 2023 rising PSA after treatment

Best wishes.

REPLY

My tx for BCR was radiation to the whole prostate area (WPRT) together with pelvic lymph nodes and 4 mos of ADT.
Not pleasant; side effects resolved over time.

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@michaelcharles

Not really enough information.
Have you been diagnosed with BCR?
See:
SPPORT trial

PCF.org video Jan 2023 rising PSA after treatment

Best wishes.

Jump to this post

Yes. PSMA .2

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@michaelcharles

My tx for BCR was radiation to the whole prostate area (WPRT) together with pelvic lymph nodes and 4 mos of ADT.
Not pleasant; side effects resolved over time.

Jump to this post

How long ago? How r u now?

REPLY
@michaelcharles

Not really enough information.
Have you been diagnosed with BCR?
See:
SPPORT trial

PCF.org video Jan 2023 rising PSA after treatment

Best wishes.

Jump to this post

PSMA pet results?

REPLY
@rkurtzjr

How long ago? How r u now?

Jump to this post

Salvage treatment (tx) began in Feb 2023 with ADT Orgovyx thru June.
37 IMRT radiation txs March - May.
Radiation side effects (SEs) resolved 3 - 4 wks after completion of therapy.
Orgovyx SEs 90 - 95% resolved 4 mos after tx.

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@rkurtzjr

PSMA pet results?

Jump to this post

PSMA PET scan preop showed cancer in prostate; questionable but not positive for pelvic lymph nodes.
2d Scan after RP and before salvage tx negative (PSA low; scans 20 - 30% accurate at PSA below .2)
Belief w/ neg scans with rising PSA is that residual cancer cells in prostate bed area and possibly pelvic lymph nodes.
See SPPORT trial

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I had RP which included tests in 8 lymph nodes. In one node, a g 3+4 Tp2 was found. To address this problem, 39 radiation treatments and Lupron shots for 24 months were suggested. Ugh. I decided to combat this instead with a plant based diet and exercise. I’ve had my PSA tested every three months for the past two years. The good news is, it has been in remission and undetectable. I’m grateful for the research that showed this as another way to improve.

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