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@livedinrochester

My Mom also took DES from Mayo with me in 1951. Around 1974/1975 my Mom got a letter asking about me and I went to Mayo for a "stain" of some kind with doctors looking inside my vagina. Nothing came of it. Pap test, pelvic exams every year after (not at Mayo) and all ok. Never wanted kids so I have no experience with fertility as a DES daughter.
Now at 72, I have depression that I now see could be from DES. In looking at articles about DES daughters, I am seeing other possible things that could happen: pancreatic cancer, (!) breast cancer. Oh, and I have had HOT FLASHES for 22 YEARS! Used BHRT and that worked but I got nervous of the Estradiol for all these years and went off. HOT FLASES back. Could this be because of DES? Cannot seem to see anything about that.

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Replies to "My Mom also took DES from Mayo with me in 1951. Around 1974/1975 my Mom got..."

Your symptoms are similar to mine. I’m 66 y/o and have been having hot flashes for at least 15 years now, longer than typical menopause. I have always suffered from depression and anxiety which runs in my family. Now, I wonder whether it is exacerbated by my DES connection. Anyone on good meds they would recommend. I have been on Zoloft and Trazadone for years.