I’ve been on Lupron for almost two years now. Thankfully I just had my last four month shot and I’m hopeful that I will get some relief soon. The side effects are problematic and that includes fatigue, loss of strength and stamina, depression and lack of motivation just to name a few. I’m a full time self employed farmer and rancher and it’s been a real struggle to keep my operation going. I’ve suffered financial losses as a result of my inability to keep up. But I am also dealing with other health issues that are far worse than the prostate cancer. I mostly work alone every day with some occasional part time help. It helps to get adequate sleep at night and I take breaks throughout the day, especially during the cold weather and blizzard conditions we have been getting lately. I can certainly sympathize with anyone who is getting Lupron or other similar hormone treatments!