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@dadcue

There are several theories about who are most at risk of PMR.
https://www.arthritis-health.com/types/polymyalgia-rheumatica/risk-factors-and-possible-causes-polymyalgia-rheumatica#:~:text=Several%20potential%20causes%20for%20PMR,giant%20cell%20arteritis%20occur%20together.
I definitely think Covid and/or the vaccine are possible triggers.

I had some success with Methotrexate (MTX) when my rheumatologist wanted me to try it. I would say MTX allowed me to decrease my prednisone. Unfortunately my liver enzymes increased as my prednisone dose decreased. Overall, MTX just made me sick. Don't let me discourage you. I firmly believe you never know what treatmen might help you unless you try it to see.

Sweating and hot flushes happen to many people. It is likely a side effect from prednisone.

For your Dad to have PMR for 20 years seems like a long time. PMR is supposed to go away after a few years. There is a "proven genetic link" to many types of inflammatory arthritis. Those disorders never completely go away and tend to relapse and become chronic conditions.

I was diagnosed with inflammatory arthritis at the age of 32. When I turned 52 there was nothing that prevented me from having PMR in addition to inflammatory arthritis. Your diagnosis is what a doctor says it is. However, one autoimmune disorder is very difficult to distinguish from another autoimmune disorder. It is also difficult to know what treatment will work.

I do know that the longer I was on prednisone, the more fatigue I felt. This was probably caused by chronic inflammation and/or a prednisone side effect that caused adrenal insufficiency. Basically, the longer I stayed on daily prednisone, (13 years), the worse I felt. I'm off prednisone now and I feel infinitely better.

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Replies to "There are several theories about who are most at risk of PMR. https://www.arthritis-health.com/types/polymyalgia-rheumatica/risk-factors-and-possible-causes-polymyalgia-rheumatica#:~:text=Several%20potential%20causes%20for%20PMR,giant%20cell%20arteritis%20occur%20together. I definitely think..."

Wow, 13 years, that's crazy. I can't imagine. I've been on prednisone for just 8+ months, am due to get to 0 in 18 days, and I hope I'm at zero for a long time. I'm constantly tired. I've been drinking coffee almost every day and I don't even like coffee. I'm very much looking forward to possibly getting better sleep. But at the end of the day, I'll take bad sleep forever over PMR pain all day every day 🙂