Just to add if you have epilepsy, tramadol can cause seizures so not the best for us. My aunt had one seizure once during childbirth and was told she could never take Tramadol. Just putting that out there. It is also addicting of course but its the only pain killer I can take tho last I took it, I got hives so I.may be out of all options gor psin.meds except toridol at home injections a few times a year. Its an anti-inflamatory, not particularly safe but can leave me 100% pain free for 24 hours - which feels magical the 4 times a year I let myself have a shot. Hello excedrine. Works when I have to take the edge off. I have fibro but my real pain issue is mainly CRPS.