@hellab Ouch, what a way to get through each day. Actually, not getting through very comfortably, right?!

Has your husband taken a look at what his meds and supplements are? His electrolytes may be out of balance, likewise high levels of calcium, phosphorous, etc. From the National Kidney Foundation, here is a very informative article that will probably answer many of your questions: https://www.kidney.org/atoz/content/chronic-kidney-disease-associated-pruritus-itchy-skin#:~:text=CKD%2DaP%20is%20very%20itchy,has%20been%20associated%20with%20itching.

What stage is your husband in for chronic kidney disease? I am on daily dialysis, and some days experience the itching you talk about. I tend to go to a more conservative resolution, looking at my labs to see if something is amiss, checking my diet, using rich creams, even a shower gel like Neutrogena Rainbath rather than soap. Often it is a trial-and-error, because sometimes one thing works, another time it is something else. I don't want to add any medications to me laundry list of prescriptions, so I steer clear from steroids.

And, it will never hurt to ask a dermatologist for their input, after explaining the situation! Good luck and let me know what you decide to do/find out!
Ginger