I saw some people using the cold for the hair loss at the chemo center but do not know how much it helped her. I must say that the woman had hair to her waist or longer but the cap needs to be up on the scalp. I also talked with a woman who wore those things on her hands & feet. She brought them in a cooler type thing already frozen & the nurse helped her fasten the 2nd hand one on. The patient got them from a friend. She thought they might have helped.