And as Rick knows we are all different:). Arikayce was easy peasy for me to take with few outward side effects. The Big 3 were a no bueno for me. I could only tolerate Azithromycin or its counterpart Clarithromycin. I think we have to just try what the doctor suggests. Hot tubs are not good for us, but my understanding is the outdoor kind may be ok. We had one that came with our home, but we emptied it and will probably have it dismantled. (irene5)