I just started a break after 44 treatments with gemcitabine/Abraxane. I have neuropathy with numbness & tingling in my hands but mostly in my feet and ankles. Occasionally I experience stabbing pains to toes or ankles. Gabapentin did not help; Lyrica was not much relief either & I experienced swelling in my feet and lower legs which disappeared after discontinuing. Acupuncture, massaging my feet and ankles with lotion and foot baths seem to help some but most of this occurs at bedtime and then I take some pain meds which calm it enough to sleep. My feet get really cold; feel like ice, and at times are icy to the touch. Someone would make a fortune if they could develop something to alleviate this CIPN!