Folfirinox seems to get almost everyone with the chemo-induced peripheral neuropathy (CIPN).
It can get worse for a while after stopping chemo -- a phenomenon called "coasting."
After 12 rounds of Folfirinox, it took about 7 months for mine to fully resolve. My neuropathy was only tingling and decreased sensation (Grade 2) -- never painful or grade 3+. (Worse now after 25 rounds of Abraxane & Cisplatin, but still grade 2).
Vitamins B6 and B12 are said to help with the lower grades, but can actually make neuropathy worse if taken in large quantities. Foot massage, foot baths, and other comforting stimulus may also provide some relief, but time seems to be the key.
If the neuropathy is painful, there are pharmaceutical options that can mask it and reduce the sensitivity, but are not necessarily curative.
You can get a cream with ketamine + amytryptaline+ lidocane, or pills like Cymbalta, Lyrica, gabapentin, mirogabalin, etc -- probably from a neurologist or palliative oncologist -- if necessary.
Thank you for sharing all your information. You are a brave soul to go through so many treatments. We wish you better times this year. I have ordered a foot massager and he’s using light compression socks now. For some reason his feet/ankles swelled last week. We see the Oncologist on Monday to review 3 month tests. That in itself is so scary. Life is so different now since being diagnosed last January. God bless.