I use Restasis twice a day for dry eye (part of Sjögren’s syndrome). It was prescribed by my brother-in- law who is an ophthalmologist in Anchorage, Alaska. It works well for me but not for my sister who also has Sjogren’s. We are all very individual with so many different variables. It’s hard to even imagine all the factors that make us the way we are. That explains our differences in our reactions to various medications.