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Metastatic breast cancer: Anyone else?

Breast Cancer | Last Active: Mar 12 3:44pm | Replies (213)

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@leighhall

Hi! I have the same problem as you. I had mastectomy in 2014. No radiation or chemo, took tamoxifen about 3 years. It caused too many side affects at work. I started having problems 3 years ago. The doctor checked for heart problems, no checking for cancer even when I told him it didn’t feel like a heart problem. He knew I had breast cancer but never checked for that. Symptoms kept getting worse, went to a different doctor 4 months later & she ran a whole bunch of tests and found Mets to lungs , ribs, spine, hips. I was on Ibrance & Letrozole for over a year & a half until it quit working. They tested me & found out the cancer had a Pik3CA mutation. I am now in a stage 1 clinical trial of a drug that targets it. I have been on it about a month, no side effects yet. Hopefully it works. Only my close family members know about my diagnosis no one to really discuss things with. I don’t want my family to worry about it. Doing ok otherwise.

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Replies to "Hi! I have the same problem as you. I had mastectomy in 2014. No radiation or..."

Hi @leighhall, that's amazing that the stage 1 clinical trial drug is not (yet) causing any side effects. Do you know the name of the drug or the clinical trial? I'd be interested in learning more. It sounds like it might be a targeted therapy for Pik3CA specific mutation. Is it?