My experience with Atorvastatin and Ezetimibe: I was put on atorvastatin 80mg daily when I had a stroke January 1, 2022. Stroke-unknown cause, I’ve had a loop recorder implant since then and there is no Afib. I have had a cardiomyopathy with reduced ejection fraction (CMP rEF) diagnosed 2002 as viral induced. My arteries have been determined normal and clear of restrictions/plaque in repeated cardiac caths over the years. However my LDL was somewhat elevated ( in the near optimal range) and the docs wanted it really low hence the atorvastatin (and such a high dose -80-omg!). 6 weeks later I saw a clinic provider in cardiology and told him I was experiencing muscle fatigue and pain increasingly in my legs. Lower down toward feet was more pain. He reduced it to 40mg. 3 weeks later I suffered a complete Achilles tendon rupture. My foot was literally disconnected from my calf muscle. Helluva recovery. 2 months later I was in a neurology apt and the doc said the tendon rupture is a rare side effect of atorvastatin (maybe any statin I dont know) and ordered off of it immediately. Later on cardiology decided to try Ezetimibe as mentioned earlier in this thread. Within 2 days I had tingling down my legs, worse at my feet and overall feeling of inflammation. No go on that one either. I’m off of cholesterol lowering meds now and hope for the best. My HDL is nice and hi and triglycerides are low so I can’t stress over it.