P1NP number on Tymlos
After 3 months on Tymlos, my P1NP bone marker has increased by 50% to 109. I was initially excited, but am wondering if this is excessive. Anyone else had numbers like this?
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maryaj7,
very exciting. 30% is satisfying; 50% is excellent. What is your CTX doing, just out of curiosity. It took me six months and then I wasn't qute 50%. I've been off Forteo this month and am curious what P1NP will indicate. I hope you keep posting the numbers.
Congratulations.
Thanks for your response! My CTX score hasn't been reported yet, but I will post when it does. I am also dealing with extreme excess calcium in my 24 hour urine test and have skipped the past two days of shots until I hear from my doctor, so I don't know if I'll even be able to stay on the Tymlos. Regarding P1NP, I just read that it peaks at about 93% above baseline at one month, and then slowly recedes. So my 50% at three months isn't excessive after all. I'm not sure how this correlates with Forteo, but I would think that it's similar. Did you have your P1NP checked before the six month mark as well? From what I read, your P1NP would have been at the highest at the one month mark. Regarding the CTX, the Tymlos literature indicates that CTX would be expected to increase quite a bit at first before decreasing. I did not expect that but am glad I read it before my lab result comes in.
I actually misspoke. My P1NP doubled, so it was a 100% increase. Dr. McCormick's book says P1NP peaks at about 150% by month five or six before it starts to recede. That's different than what the Tymlos site says. Still no CTX result.