Do you think maybe we are misinterpreting the doctor's response to @lilianna ?
My impression is that she is asking if she feels she can tolerate adding another drug to her already tough regimen.
Have you decided what to do? In my case, my pulmonologist decided that we had to treat the pseudomonas first, because I had a heavy colonization. Once it cleared, we started the Big-3 for MAC. I cannot imagine going through both at the same time.

@lilianna Have you decided what you are going to do?
Sue

I was diagnosed with Pseudo late September and because I could not tolerate Cipro once before I was put on IV Meropenin for 2 weeks, but it is colonized, so my doctor said I had to nebulize Tobramycin monthly which I have been doing. I felt absolutely horrible before I got help, the Meropenin helped right away, I think just time improved my health, and I'm not sure what the Tobi does except make me short of breath and anxious about the calendar waiting to start another round in addition to nebulizing Albuterol and saline twice a day every day. I am also taking Azithro 3X a week, but I do not have MAC currently. I did have MAC 10 years ago and treatment was successful with 3 antibiotics. I can only say that I am feeling better and so very thankful, as I was very sick with Pseudo. I am thinking about getting a second opinion however, as I got/get very little direction from my pulmonologist. Right now, I'm just trying to maintain. I agree that our medical system is in a sorry state. Good luck to us all.