I have done the Reclast annual IV infusion once at the 'regular" dose. I took Tylenal pre infusion, lots of water and slow infusion(about 40 min). Now 3 months out I still have bone groin pain both sides that I never had before. The doctor thought it would go away after a month post infusion, it has not gone away. I take 2,000 to 3,000 mg of tylenal a day now in order to manage this. I have not ruled out joint arthrititis but this pain feels different then that to me.
Is this pain from Reclast helping me or not? I don't know .
I have 2 friends that take Reclast annual infusions without any problem.
Fosamax gave me esophageal issues.
So maybe I am one of those folks that have issues with meds.
Good Luck