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Chemo or Not after oophorectomy

Gynecologic Cancers | Last Active: Jan 11 8:20am | Replies (8)

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@val64

I haven't been in this exact position, but I have learned something through my experiences with endometrial cancer that may be relevant.

As far as I know, ovarian and endometrial cancers can spread in three main ways: through the bloodstream, through the lymphatic system, and directly into the inside of the abdomen (aka the peritoneum) either straight from the ovaries or via the fallopian tubes. Apparently intravenous chemotherapy drugs have access to cancer cells that have spread via the blood or lymphatic system, but mostly do not reach cancer cells that have spread into the peritoneum. I had 6 rounds of chemotherapy late last year, but recently learned that I have numerous tumors in my peritoneum. Sometimes women with ovarian cancer are treated with intraperitoneal chemotherapy during their surgery (look up "HIPEC") because if this issue.

Maybe you should ask your doctor about the likelihood of peritoneal spread in your case and whether IV chemo would be likely to help.

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Thank you so much for your reply.