I’m a 67 y/o Aussie male who has had CFS all my life. Started mainly in feet, toes, hands & fingers several times a day. It now affects those areas several times an hour. I’ve been diagnosed by to Brain & Nerve professors who have each prescribed various medications, each of which gave no relieve but only depression. As the years have gone on, other areas of my body now cramp up. Legs, arms, back, jaw, tongue, abdomen and diaphragm, the last two, though scary as it‘s difficult to breathe, they aren’t the most painful. (Cramps in the anal sphincter muscle are the most painful.) Fasciculations occur in several muscle groups continually. Both professors showed great interest when I explained that both my sons (from different mothers) also appear to suffer from CFS, yet my daughters show no signs. We, me & my sons, are undergoing genetic testing to help in the research.