I feel I need to say something about opioids and antidepressants. They don't make a person"euphoric". I've been taking both for a long time, and I definitely have never experienced anything that is close to euphoria.
If a person who has chronic (also called clinical or major) depression is taking an antidepressant, the medication helps to level out the mood. Bipolar depression and bipolar disorder are another subject. Medication helps to make the mood swings that go from dark depression to a hyper, manic high, level out so the downs don't go as far down and the high doesn't get to a manic episode.
I've been taking a fairly low dose of morphine sulfate contin for several years now, specifically for the neuropathy pain, and it has helped take the edge off the pain. I stopped taking it yesterday because I started a new medication that seems to be helping a lot. My hope is that the Imipram will treat the pain enough so I can get off opioids. I've willingly taken it because it's the only medication that has treated my pain without unacceptable side effects.