Good to hear because I went to MD Anderson after dx in Dec, 22. I have ussed Imiquimod since then and as you said the itching and burning was difficult. I now have a couple of new lesions and my Oncologist just did 5 bx under general...deep and stitches. I am 5 days post and am waiting for bx results and further information. MD said surgery can be done but does not cure. I just read someone did radiation and it sounds horrible. I am in a pool of rare cancers there but no research at this time. When I first read about this they said the cause is really unknown but read someone said HPV driven, Nope...but they did do CATS, tested for it, colonoscopy, etc. All were negative except for the bx. I appreciate hearing your story. All information helps even if we don't want to hear it!!!